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Product Name | JNJ 47965567 |
Description | Potent and selective P2X7 antagonist (pIC50 values are 8.3, 7.5 and 7.2 for human, mouse and rat receptors respectively). Selective over a panel of 50 other receptors, ion channels and transporters. Reduces BzATP -induced IL-1β release from monocytes in vitro and from rat brain in vivo. Attenuates amphetamine -induced hyperactivity in rats. Brain penetrant. Purity 98%. MW (observed): 488.64 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-(Phenylthio)-N-[[tetrahydro-4-(4-phenyl-1-piperazinyl)-2H-pyran-4-yl]methyl-3-pyridinecarboxamide |
Gene, Accession, CAS # | CAS: 1428327-31-4 |
Catalog # | 5299/10 |
Price | |
Order / More Info | JNJ 47965567 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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