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Product Name | JNJ 55511118 |
Description | High affinity and selective negative modulator of AMPA receptors containing TARP-γ8 (Ki = 26 nM). Exhibits <50% binding against a panel of 52 receptors, ion channels and transporters (except 5HT2B and melatonin receptors 78% and 57%, respectively). Also displays minimal activity against other TARP-less AMPARs and AMPARs coexpressed with other TARPs or CNIH2. Orally bioavailable and brain penetrant. Anticonvulsant. Purity 98%. MW (observed): 328.67 |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-[2-Chloro-6-(trifluoromethoxy)phenyl]-1,3-dihydro-2H-benzimidazol-2-one |
Gene, Accession, CAS # | CAS: 2036081-86-2 |
Catalog # | 6278/25 |
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Order / More Info | JNJ 55511118 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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