| 产品详情 |
| Edit |   |
|---|
| Product Name | Human IL-1 beta Recombinant Protein |
|---|
| Description | Human IL-1 beta Recombinant Protein. Interleukin-1 beta (IL-1 beta) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta is synthesized in response to inflammatory stimuli as a 31 kDa inactive pro-form that accumulates in the cytosol. Cleavage of pro-IL-1 beta into the active 17 kDa protein requires the activation of inflammasomes, which are multi-protein complexes that respond to pathogens, stress conditions, and other danger signals. Inflammasome activation triggers the processing of the caspase-1 precursor into its active form, which in turn cleaves pro-IL-1 beta. IL-1 beta lacks a signal sequence peptide for classical ER/Golgi pathway and is secreted alongside caspase-1 via an alternate and i |
|---|
| Size | 20 ug |
|---|
| Concentration | lyophilized |
|---|
| Applications | Control: Assay Dependent, ELISA: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent |
|---|
| Other Names | IL-1 beta; catabolin; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta; IL-1beta |
|---|
| Gene, Accession, CAS # | Entrez: 3553; Uniprot: P01584 |
|---|
| Catalog # | RIL1BI |
|---|
| Price | |
|---|
| Order / More Info | Human IL-1 beta Recombinant Protein from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|