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| Product Name | Human IL-1 beta Recombinant Protein |
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| Description | Human IL-1 beta Recombinant Protein, eBioscience™. Interleukin-1 beta (IL-1 beta) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta is synthesized in response to inflammatory stimuli as a 31 kDa inactive pro-form that accumulates in the cytosol. Cleavage of pro-IL-1 beta into the active 17 kDa protein requires the activation of inflammasomes, which are multi-protein complexes that respond to pathogens, stress conditions, and other danger signals. Inflammasome activation triggers the processing of the caspase-1 precursor into its active form, which in turn cleaves pro-IL-1 beta. IL-1 beta lacks a signal sequence peptide for classical ER/Golgi pathway and is secreted alongside caspase-1 vi |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Control: Assay-Dependent, ELISA: Assay-Dependent, Functional Assay: Assay-Dependent |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Entrez: 3553; Uniprot: P01584 |
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| Catalog # | 14-8018-80 |
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| Order / More Info | Human IL-1 beta Recombinant Protein from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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