Edit |   |
Antigenic Specificity | NCF4 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunohistochemistry: 2-4 µg/mL, peptide-ELISA: 1:32000, Western Blot: 0.3-1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NCF4 Polyclonal Antibody. The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 to form a complex with neutrophil cytosolic factor 1 kinase, which suggests its role in PIkinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
Immunogen | n/a |
Other Names | NCF4; P40PHOX; neutrophil cytosolic factor 4, 40kDa ; CTA-833B7.1; MGC3810; NCF; SH3PXD4; OTTHUMP00000028736; OTTHUMP00000043756; neutrophil NADPH oxidase factor 4; neutrophil cytosol factor 4; neutrophil cytosolic factor 4 (40kD) |
Gene, Accession # | Entrez: 4689; Uniprot: Q15080 |
Catalog # | PA5-18751 |
Price | |
Order / More Info | NCF4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |