| 产品详情 |
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| Product Name | BLMH, 1-455aa, Mouse, His-tag, E.coli (Bioactivity Validated) |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl(pH8.0) containing 1mM DTT, 0.1M NaCl, 30% Glycerol. BLMH, also known as bleomycin hydrolase, is a member of the papain superfamily of the cysteine protease and the peptidase C1 family. It is a cytoplasmic cysteinepeptidase commonly found as a homohexamer. The normal physiological role of BLMH is unknown, but it protects normal and malignant cells from the glycopeptide antitumor drug Blm. It catalyzes the inactivation of the antitumor drug Blm (a glycopeptide) by hydrolyzing the carboxyamide bond of its B-aminoalaninamide moiety and also shows general aminopeptidase activity. Recombinant mouse BLMH protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 50ug, 10ug, |
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| Concentration | n/a |
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| Applications | SDS-PAGE,Enzyme Activity |
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| Other Names | Bmh, Bh, Blm hydrolase, bleomycin hydrolase, AI035728, Bleomycin hydrolase, Blm hydrolase, Blmh, EC 3.4.22.40 |
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| Gene, Accession, CAS # | NP_848760 |
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| Catalog # | ATGP3880 |
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| Order / More Info | BLMH, 1-455aa, Mouse, His-tag, E.coli (Bioactivity Validated) from ATGen |
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| Product Specific References | n/a |
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