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| Product Name | CyPPA |
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| Description | Purity >98%. CyPPA is a positive modulator of the small conductance calcium-activated potassium channels SK2 and SK3 (EC50 s = 14 and 5.6 µM, respectively). It is inactive on both SK1 and the intermediate conductance calcium-activated potassium channel, IK. At SK3, CyPPA increases the apparent calcium-sensitivity of channel activation, changing the EC50 value of calcium activation from 429 to 59 nM. CyPPA is used to evaluate the roles of SK2 and SK3 in such diverse processes as memory encoding, uterine muscle contraction, and dopamine signaling. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methyl-4-pyrimidinamine |
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| Gene, Accession, CAS # | CAS: 73029-73-9 |
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| Catalog # | LS-H7311 |
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| Order / More Info | CyPPA from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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