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Product Name | A 83-01 |
Description | MW: 421.52. Purity ≥98% by HPLC. Background: A selective inhibitor of TGF-beta type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC?? values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-beta-induced epithelial-to-mesenchymal transition. Helps maintain homogeneity and long-term in vitro self-renewal of human induced pluripotent stem cells (iPSCs). |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | [3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-p yrazole-1-carbothioamide] |
Gene, Accession, CAS # | CAS: 909910-43-6 |
Catalog # | MBS842636 |
Price | |
Order / More Info | A 83-01 from MYBIOSOURCE INC. |
Product Specific References | n/a |
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