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| Product Name | A-1331852 |
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| Description | An orally bioavailable Bcl-xL inhibitor; selectively binds Bcl-xL over Bcl-2, Mcl-1, and Bcl-W (Kis = in vitro (EC50s = 6 and >5,000 nM, respectively); inhibits tumor growth in a MOLT-4 mouse xenograft model at 25 mg/kg; inhibits tumor growth and increases the antitumor activity of docetaxel in MDA-MB-231 LC3 metastatic breast cancer and NCI-H1650 non-small cell lung cancer mouse xenograft models at 25 mg/kg |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | A1331852 BclXL MOLT4 bcl2 RS411 MDAMB231 MB231 LC-3 NCIH1650 NCIH1963 |
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| Gene, Accession, CAS # | CAS: 1430844-80-6 |
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| Catalog # | 22963-1 |
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| Price | |
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| Order / More Info | A-1331852 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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