| 产品详情 |
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| Product Name | MIM1 |
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| Description | Inhibitor of Mcl-1. Inhibits Mcl-1 indirectly by induction of the proapoptotic Mcl-1 ligand NOXA via the unfolded protein response (UPR) pathway. Sensitizes leukemia cells to the Bcl-2 inhibitor venetoclax (ABT-199). Induces caspase-3/7 activation and cell death in Mcl-1-dependent leukemia cells. Also blocks Mcl-1-mediated suppression of tBID-induced Bax activation in vitro. MW (observed): 347.43. |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-(E)-[[(2Z)-2-cyclohexylimino)-4-methyl-1,3-thiazol-3(2H)-yl]imino]methyl]benzene-1,2,3-triol |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 4762/50 |
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| Price | |
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| Order / More Info | MIM1 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 25032861 |
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| 产品资料 |
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