产品详情 |
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Antigenic Specificity | CTLA4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100ug (sample available) |
Concentration | 500ug/ml. |
Applications | ELISA, IHC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal Picoband™ antibody for Cytotoxic T-lymphocyte protein 4(Ctla4) detection. Tested with WB, IHC-P, ELISA in Mouse;Rat. No cross reactivity with other proteins. CTLA-4(Cytotoxic T-Lymphocyte Antigen 4), also known as CD152, is a protein receptor that down regulates the immune system. It is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Blockade of CTLA4 expression in vitro augmented HIV-specific CD4-positive T-cell function. |
Immunogen | E. coli-derived mouse CTLA4 recombinant protein (Position: E36-D161). Mouse CTLA4 shares 67.5% amino acid (aa) sequence identity with human CTLA4. |
Other Names | Cytotoxic T-lymphocyte protein 4;Cytotoxic T-lymphocyte-associated antigen 4;CTLA-4;CD152;Ctla4;Cd152; |
Gene, Accession # | Ctla4, UniProt: P09793 |
Catalog # | A00020-1 |
Price | |
Order / More Info | CTLA4 Antibody from BOSTER BIO |
Product Specific References | n/a |
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