| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CTLA-4 |
|---|
| Clone | A3.4H2.H12 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG2a, kappa |
|---|
| Format | fluorescein (FITC) conjugate |
|---|
| Size | 100 ug |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 1.0 µg/1x10^6 cells |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CTLA-4 Monoclonal Antibody (A3.4H2.H12), FITC. CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. |
|---|
| Immunogen | n/a |
|---|
| Other Names | CD152, CELIAC3, CTLA-4, GRD4, GSE, ICOS, IDDM12, CD152 isoform, celiac disease 3, cytotoxic T lymphocyte associated antigen 4 short spliced form, cytotoxic T-lymphocyte antigen 4, cytotoxic T-lymphocyte protein 4, cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated serine esterase-4 |
|---|
| Gene, Accession # | Entrez: 1493; Uniprot: P16410 |
|---|
| Catalog # | MA5-17732 |
|---|
| Price | |
|---|
| Order / More Info | CTLA-4 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|