产品详情 |
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Antigenic Specificity | MAGED1 |
Clone | 353124 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2B |
Format | purified |
Size | 100 µg |
Concentration | lyophilized |
Applications | Flow Cytometry: 2.5 µg/1x10^6 cells, Immunocytochemistry: 8-25 µg/mL, Immunofluorescence: 8-25 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MAGED1 Monoclonal Antibody (353124). MAGE-D2, also known as Melanoma-associated antigen D2, belongs to the melanoma antigen encoding gene (MAGE) family with a MAGE domain. Rat and mouse orthologues have been isolated. Compared to other proteins (MAGE-A, MAGE- B and MAGE-C clusters) MAGE-D2 is expressed ubiquitously. This intracellular protein shows high expression in specific brain regions and in the interstitium of testes. Though the exact function of this protein is yet to be deduced, MAGE-D2 is considered as a hot spot for X-linked mental retardation. Research reveals that MAGE-D2 might have some role in breast and gastric cancer, as well as in hepatocellular carcinoma. MAGE-D2 is also known to interact physically with p53 and modify its |
Immunogen | n/a |
Other Names | Maged1, Maged2, PP2250, PRO2292, NRAGE, Melanoma-associated antigen D1, MAGE tumor antigen CCF, MAGE-D1 antigen, Neurotrophin receptor-interacting MAGE homolog, 11B6, Breast cancer-associated gene 1 protein, BCG-1, JCL-1, Melanoma-associated antigen D2 |
Gene, Accession # | Entrez: 9500; Uniprot: Q9Y5V3 |
Catalog # | MA5-24096 |
Price | |
Order / More Info | MAGED1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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