产品详情 |
Edit |   |
Antigenic Specificity | TIM3 |
Clone | 25F.1D6 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, kappa |
Format | fluorescein (FITC) conjugate |
Size | 100 ug |
Concentration | n/a |
Applications | Flow Cytometry: 1 µg /1x10^6 cells, Immunohistochemistry: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TIM3 Monoclonal Antibody (25F.1D6), FITC. TIM3 (Hepatitis A virus cellular receptor 2, HAVCR2, T-cell immunoglobulin, mucin-dmain containing-3) is a 281 amino acid long, Type-1 Th1- specific cell surface glycoprotein expressed on terminally differentiated CD4+Th1 and CD8+Tc1 cells. TIM3 consists of an IgV-like domain, a mucin-like domain in the extracellular region, and a conserved Tyrosine phosphorylation motif in the cytoplasmic region. TIM3 is involved in macrophage activation and induction of autoimmune diseases. Further, TIM3 down-regulates aggressive Th1-mediated immune responses and facilitates in the development of immune tolerance. Pathological significance of TIM3 has been attributed to Experimental autoimmune encephalomyelitis (E |
Immunogen | n/a |
Other Names | HAVCR2, hepatitis A virus cellular receptor 2, FLJ14428, KIM-3, TIMD3, T cell immunoglobulin mucin 3, kidney injury molecule 5 |
Gene, Accession # | Entrez: 171285; Uniprot: Q8VIM0 |
Catalog # | MA5-17957 |
Price | |
Order / More Info | TIM3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
|
|