| 产品详情 |
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| Antigenic Specificity | TIM3 |
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| Clone | 25F.1D6 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, kappa |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 50 ug |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1 µg /1x10^6 cells |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TIM3 Monoclonal Antibody (25F.1D6), PE. TIM3 (Hepatitis A virus cellular receptor 2, HAVCR2, T-cell immunoglobulin, mucin-dmain containing-3) is a 281 amino acid long, Type-1 Th1- specific cell surface glycoprotein expressed on terminally differentiated CD4+Th1 and CD8+Tc1 cells. TIM3 consists of an IgV-like domain, a mucin-like domain in the extracellular region, and a conserved Tyrosine phosphorylation motif in the cytoplasmic region. TIM3 is involved in macrophage activation and induction of autoimmune diseases. Further, TIM3 down-regulates aggressive Th1-mediated immune responses and facilitates in the development of immune tolerance. Pathological significance of TIM3 has been attributed to Experimental autoimmune encephalomyelitis (EAE |
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| Immunogen | n/a |
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| Other Names | HAVCR2, hepatitis A virus cellular receptor 2, FLJ14428, KIM-3, TIMD3, T cell immunoglobulin mucin 3, kidney injury molecule 6 |
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| Gene, Accession # | Entrez: 171285; Uniprot: Q8VIM0 |
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| Catalog # | MA5-17958 |
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| Price | |
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| Order / More Info | TIM3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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