产品名称 CD20 (human) Antibody from PENINSULA LABORATORIES INTERNATIONAL, INC.
产品货号 T-1371.0100
产品价格 现货询价,电话:010-67529703
产品规格 100 ug
产品品牌 PENINSULA LABORATORIES INTERNATIONAL, INC.
产品概述
产品详情
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Antigenic SpecificityCD20 (human)
CloneCAT13.6E12
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a
Formatpurified
Size100 ug
Concentrationn/a
ApplicationsIHC, FACS
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DescriptionIntermediate differentiation stage B-cell marker. Monoclonal antibody CAT13.6E12 recognizes the CD20 antigen. CD20 belongs to the MS4A family (membrane-spanning 4-domains subfamily A). Its expression is restricted to normal and neoplastic B-cells. It is expressed by pre-B-cells in the bone marrow, and expression persists during B-cell maturation but is lost upon terminal differentiation into plasma cells. CD20 is not glycosylated. CD20 is not phosphorylated in resting B-cells, but becomes heavily phosphorylated after mitogen stimulation. Three cell surface isoforms 33, 35 and 37kD, result from differential phosphorylation of a single core 33kD protein within the cytoplasmic domain. Multiple proteins are coimmunoprecipitated with CD20, suggesting that it may be a component of a multimeric surface receptor complex. Monoclonal antibodies against CD20 are used therapeutically, such as Rituximab (Mabthera) or Britumomab (Zevalin). Application: IHC (f), FACS
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #T-1371.0100
Price
Order / More InfoCD20 (human) Antibody from PENINSULA LABORATORIES INTERNATIONAL, INC.
Product Specific Referencesn/a
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