产品详情 |
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Antigenic Specificity | Calbindin D28K |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | lyophilized |
Applications | ELISA: Assay dependent, Immunohistochemistry (Paraffin): 1 µg/mL, Immunoprecipitation: 5 µg/mL, Western Blot: 2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Calbindin D28K Polyclonal Antibody. Vitamin D-dependent 28 kDa calcium-binding protein (calbindin D 28k or CB) is a member of the calmodulin superfamily of calcium binding proteins discovered in 1966 by Wasserman and Taylor. The protein has a distinct distribution in the brain and sensory system and is abundant in specific neuronal cell types. Calbindin D-28k constitutes as much as 0.1-1.5 % of the total soluble protein in brain and it may be present at intracellular concentrations up to 1 mM. Several recent studies have shown that calbindin D can protect cells from degeneration and ischemic injury under extracellular stress. In particular, this is demonstrated in the brain of Alzheimer's disease patients. Cells containing calbindin D have |
Immunogen | n/a |
Other Names | Vitamin D-Dependent 28 kDa Calcium-Binding Protein , CB |
Gene, Accession # | Entrez: 12307, 793, 83839; Uniprot: P05937, P07171, P12658 |
Catalog # | PA1-931 |
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Order / More Info | Calbindin D28K Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 25885452 |
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