| 产品详情 |
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| Antigenic Specificity | TRAF6 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | 0.5 mg/ml |
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| Applications | Western blot |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TRAF6 Antibody. TRAFs (TNF receptor associated proteins) form a family of cytoplasmic adapter proteins that mediate signal transduction from many members of the TNF-receptor superfamily and the interleukin-1 receptor. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. Recent molecular cloning studies have lead to identification of six TRAFs (TRAF1-TRAF6). Recently it has been shown that TRANCE/OPGL activates the antiapoptotic serine/threonine kinase Akt/PKB throµgh a signaling complex involving c-Src and TRAF6. Mice deficient in TRAF6 are osteopetrotic with defects in bone remodeling and tooth eruption due to impaired osteocl |
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| Immunogen | Synthetic peptide surrounding amino acid 436 of rat TRAF6 |
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| Other Names | TRAF6 , RNF85 , MGC:3310 |
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| Gene, Accession # | Gene ID: 311245, Accession: NP_001101224 |
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| Catalog # | 3566R-100 |
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| Price | |
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| Order / More Info | TRAF6 Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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