产品详情 |
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Antigenic Specificity | ARS2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, zebrafish |
Isotype | n/a |
Format | purified |
Size | 200 µl |
Concentration | n/a |
Applications | Western Blot: 1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ARS2 Polyclonal Antibody. Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs (By similarity). Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity). |
Immunogen | n/a |
Other Names | Serrate RNA effector molecule homolog; Arsenite-resistance protein 2; srrt; ars2 |
Gene, Accession # | Entrez: 192311, 51593; Uniprot: Q66I22, Q9BXP5 |
Catalog # | PA5-72269 |
Price | |
Order / More Info | ARS2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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