| 产品详情 |
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| Antigenic Specificity | BACE2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:10-1:200, Immunofluorescence: 1:10-1:200, Western Blot: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | BACE2 Polyclonal Antibody. BACE2 or Beta Secretase 2 is responsible for the proteolytic processing of the amyloid precursor protein (APP). BACE2 cleaves APP between residues 690 and 691. This cleavage leads to the generation and extracellular release of beta-cleaved soluble APP. BACE2 is also know to cleave APP between residues 671 and 672. Accumulation of APP is a signature of Alzheimer disease and frequent complication of adult Down syndrome patients. |
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| Immunogen | n/a |
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| Other Names | BACE2, Beta-Site APP-Cleaving Enzyme 2, Aspartyl protease 1, Asp 1, ASP1, Membrane-associated aspartic protease 1, Memapsin-1, Down region aspartic pr |
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| Gene, Accession # | Entrez: 25825, 56175; Uniprot: Q9JL18, Q9Y5Z0 |
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| Catalog # | PA1-754 |
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| Price | |
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| Order / More Info | BACE2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10531052 |
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