产品详情 |
Edit |   |
Antigenic Specificity | BACE2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunohistochemistry: Assay-dependent, Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BACE2 Polyclonal Antibody. BACE2 or Beta Secretase 2 is responsible for the proteolytic processing of the amyloid precursor protein (APP). BACE2 cleaves APP between residues 690 and 691. This cleavage leads to the generation and extracellular release of beta-cleaved soluble APP. BACE2 is also know to cleave APP between residues 671 and 672. Accumulation of APP is a signature of Alzheimer disease and frequent complication of adult Down syndrome patients. |
Immunogen | n/a |
Other Names | AEPLC, ALP56, ASP1, ASP21, BAE2, CDA13, CEAP1, DRAP |
Gene, Accession # | Entrez: 25825, 288227, 56175; Uniprot: Q6IE75, Q9JL18, Q9Y5Z0 |
Catalog # | PA1-30765 |
Price | |
Order / More Info | BACE2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
|
|