产品详情 |
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Antigenic Specificity | BACE2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunohistochemistry: 2 µg/mL, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BACE2 Polyclonal Antibody. BACE2 or Beta Secretase 2 is responsible for the proteolytic processing of the amyloid precursor protein (APP). BACE2 cleaves APP between residues 690 and 691. This cleavage leads to the generation and extracellular release of beta-cleaved soluble APP. BACE2 is also know to cleave APP between residues 671 and 672. Accumulation of APP is a signature of Alzheimer disease and frequent complication of adult Down syndrome patients. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 25825, 288227; Uniprot: Q6IE75, Q9Y5Z0 |
Catalog # | PA5-19951 |
Price | |
Order / More Info | BACE2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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