| 产品详情 |
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| Antigenic Specificity | Estrogen Receptor beta |
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| Clone | 14C8 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ChIP assay: Assay dependent, Flow Cytometry: Assay dependent, Immunocytochemistry: Assay dependent, Immunofluorescence: Assay dependent, Immunohistochemistry (Paraffin): 1-5 µg/mL, Western Blot: 1-5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Estrogen Receptor beta Monoclonal Antibody (14C8). Estrogen Receptor beta (ER beta, NR3A2) protein is approximately 55kD, though multiple isoforms ranging from 36-59kD have been described. Human ER beta was initially cloned and characterized from testis. Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors. The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA. When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins. There are two different f |
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| Immunogen | n/a |
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| Other Names | ER Beta, ER, ESR2, ESR-Beta |
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| Gene, Accession # | Entrez: 13983, 2100; Uniprot: O08537, Q92731 |
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| Catalog # | MA1-23217 |
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| Price | |
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| Order / More Info | Estrogen Receptor beta Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 18048642, 27006379 |
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