产品名称 Human CD80 Antibody from CREATIVE DIAGNOSTICS
产品货号 CABT-L900
产品价格 现货询价,电话:010-67529703
产品规格 n/a
产品品牌 CREATIVE DIAGNOSTICS
产品概述
产品详情
Edit&nbsp
Antigenic SpecificityHuman CD80
CloneKG21-5
Host SpeciesRabbit
Reactive Specieshuman
IsotypeIgG
Formatunconjugated
Sizen/a
Concentrationn/a
ApplicationsWB, IHC
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionRabbit Anti-Human CD80 monoclonal antibody for WB, IHC. T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells, bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counterreceptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.
ImmunogenRecombinant Protein
Other Namesn/a
Gene, Accession #Gene ID: 941, UniProt: A0N0P2
Catalog #CABT-L900
Price
Order / More InfoHuman CD80 Antibody from CREATIVE DIAGNOSTICS
Product Specific Referencesn/a
产品资料