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Antigenic Specificity | Sortilin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Cy3 conjugate |
Size | 100ul |
Concentration | 1ug/ul |
Applications | IF(IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Sortilin Polyclonal Antibody, Cy3 Conjugated. • Target Background: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensi |
Immunogen | KLH conjugated synthetic peptide derived from human Sortilin. Immunogen Range: 705-755/831 |
Other Names | NT3; Gp95; LDLCQ6; Sortilin; 100 kDa NT receptor; Glycoprotein 95; Neurotensin receptor 3; NTR3; SORT1 |
Gene, Accession # | Gene ID: 6272, SwissProt: Q99523 |
Catalog # | bs-6329R-Cy3 |
Price | |
Order / More Info | Sortilin Antibody from BIOSS ANTIBODIES |
Product Specific References | Paik et al. (2018) Sci.Rep. 8:804. PubMed: 29339826 |