产品详情 |
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Antigenic Specificity | Cytokeratin 8 |
Clone | 3G9 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2b |
Format | unconjugated |
Size | 100ug |
Concentration | 0.5-1mg/ml, actual concentration varies by lot. |
Applications | Flow Cytometry, IHC-P, IHC-F, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse IgG monoclonal Picoband™ antibody for Cytokeratin 8 detection. Tested with WB, IHC-P, IHC-F, FCM in Human;Mouse;Rat. No cross reactivity with other proteins. Keratin, type II cytoskeletal 8, also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that is encoded in humans by the KRT8 gene. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. |
Immunogen | E.coli-derived human Cytokeratin 8 recombinant protein (Position: D107-K325). Human Cytokeratin 8 shares 95.4% and 94.5% amino acid (aa) sequence identity with mouse and rat Cytokeratin 8, respectively. |
Other Names | Keratin, type II cytoskeletal 8; Cytokeratin-8; CK-8; K8; Type-II keratin Kb8; KRT8; CYK8 |
Gene, Accession # | KRT8, UniProt: P05787 |
Catalog # | M01421-3 |
Price | |
Order / More Info | Cytokeratin 8 Antibody from BOSTER BIO |
Product Specific References | n/a |
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