| 产品详情 |
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| Product Name | A-841720 |
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| Description | A noncompetitive antagonist of mGluR1 (IC50 = 10.7 nM); selective over mGluR5 (IC50 = 343 nM), mGluR2, mGluR4, and mGluR7; selective over a panel of other G-coupled protein receptors as well as ligand- and voltage-gated ion channels at a concentration of 10 µM; dose-dependently inhibits complete Freund's adjuvant-induced inflammatory pain (ED50 = 23 µmol/kg) and sciatic nerve injury-induced mechanical allodynia (ED50 = 28 µmol/kg) in rats; enhances cocaine seeking in mice after a prolonged abstinence following a single conditioning session (10 mg/kg) |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | A814720 HEK-293 CFA mGluR |
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| Gene, Accession, CAS # | CAS: 869802-58-4 |
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| Catalog # | 21807-10 |
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| Price | |
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| Order / More Info | A-841720 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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