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Product Name | Human FLIP Synthetic Peptide |
Description | Human FLIP Synthetic Peptide. FLIP (CFLAR) is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity. |
Size | 50 ug |
Concentration | n/a |
Applications | Blocking Assay: Assay Dependent, Control: Assay Dependent |
Other Names | n/a |
Gene, Accession, CAS # | Entrez: 8837; Uniprot: O15519 |
Catalog # | PEP-0014 |
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Order / More Info | Human FLIP Synthetic Peptide from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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