产品详情 |
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Antigenic Specificity | CD86 |
Clone | K86 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 100 ug, 500 ug |
Concentration | n/a |
Applications | FACS, ICC, IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse monoclonal to CD86.CD86 also known as B7-2,is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors.It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86,along with CD80/B7-1.is an important accessory molecule in T cell costimulation via it's interaciton with CD28 and CD152/CTLA4.Since CD86 has rapid kinetics of induction.it is believed to be the major CD28 ligand expressed early in the immune response.it is also found on malignant Hodgkin and Reed Sternberg(HRS) cells in Hodgkin's disease. |
Immunogen | n/a |
Other Names | CD86 |
Gene, Accession # | n/a |
Catalog # | orb12124 |
Price | |
Order / More Info | CD86 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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