产品详情 |
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Antigenic Specificity | CD366 (TIM3) |
Clone | F38-2E2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Super Bright 600 conjugate |
Size | 100 Tests |
Concentration | n/a |
Applications | Flow Cytometry: 5 µL (0.125 µg)/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD366 (TIM3) Monoclonal Antibody (F38-2E2), Super Bright 600, eBioscience™. TIM3 (Hepatitis A virus cellular receptor 2, HAVCR2, T-cell immunoglobulin, mucin-dmain containing-3) is a 281 amino acid long, Type-1 Th1- specific cell surface glycoprotein expressed on terminally differentiated CD4+Th1 and CD8+Tc1 cells. TIM3 consists of an IgV-like domain, a mucin-like domain in the extracellular region, and a conserved Tyrosine phosphorylation motif in the cytoplasmic region. TIM3 is involved in macrophage activation and induction of autoimmune diseases. Further, TIM3 down-regulates aggressive Th1-mediated immune responses and facilitates in the development of immune tolerance. Pathological significance of TIM3 has been attributed to Expe |
Immunogen | n/a |
Other Names | CD366; HAVcr-2; HAVCR2; KIM-3; Tim-3; TIM3; TIMD-3; TIMD3 |
Gene, Accession # | Entrez: 84868; Uniprot: Q8TDQ0 |
Catalog # | 63-3109-42 |
Price | |
Order / More Info | CD366 (TIM3) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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