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| Antigenic Specificity | Acetyl-Histone H4 (Lys8) |
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| Clone | 9HCLC |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ChIP assay: 5 µg x 10^6 cells, Immunocytochemistry: 1 µg/mL, Immunofluorescence: 1 µg/mL, Peptide Array: 0.25 µg/mL, Western Blot: 0.5-1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Acetyl-Histone H4 (Lys8) Antibody (9HCLC), ABfinity™ Rabbit Oligoclonal. Histone octamers are an essential component of the nucleosomal complex with key roles in chromatin packaging and target gene transcription. They undergo various post-translational modifications including methylation, acetylation and phosphorylation to facilitate chromatin regulation. These modifications in turn serve as epigenetic markers for transcriptional status of a gene and landing sites for transcriptional complexes. The N-terminal tail of H4 undergoes acetylation regulated by histone acetyl transferases and histone deacetylases. Acetylated Histone 4 at Lysine 8 (H3K8ac) is typically enriched at positively regulated gene promoters. It is one of the most pro |
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| Immunogen | n/a |
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| Other Names | H4K8ac, HIST1H4A, H4/A, H4FA, Histone H4, Histone H4A |
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| Gene, Accession # | Entrez: 8359; Uniprot: P62805 |
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| Catalog # | 710828 |
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| Price | |
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| Order / More Info | Acetyl-Histone H4 (Lys8) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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