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Antigenic Specificity | Acetyl-p53 (Lys382) |
Clone | 10HCLC |
Host Species | Recombinant Rabbit |
Reactive Species | human, mouse |
Isotype | IgG |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ChIP assay: 2-3 µh x 10^6, Immunocytochemistry: 1-2 µg/mL, Immunofluorescence: 1-2 µg/mL, Immunohistochemistry (Paraffin): 1:20-1:100, Western Blot: 1-3 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acetyl-p53 (Lys382) Antibody (10HCLC), ABfinity™ Rabbit Oligoclonal. The tumor suppressor protein, p53, is a sequence specific transcription factor that is activated by cellular stress. p53 mediates cell cycle arrest or apoptosis in response to DNA damage or starvation for pyrimidine nucleotides. p53 is up-regulated in response to stress signals and stimulated to activate transcription of specific genes, resulting in expression of p21waf1 and other proteins involved in G1 or G2/M arrest. The structure of p53 comprises an N-terminal transactivation domain, a central DNA-binding domain, an oligomerisation domain, and a C-terminal regulatory domain. There are various phosphorylation sites on p53, of which the phosphorylation at Ser15 is |
Immunogen | n/a |
Other Names | antigen NY-CO-13, cellular tumor antigen p53, p53 tumor suppressor, phosphoprotein p53, transformation-related protein 53, TP53, FLJ92943, LFS1, TRP53 |
Gene, Accession # | Entrez: 22059, 7157; Uniprot: P02340, P04637 |
Catalog # | 710294 |
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Order / More Info | Acetyl-p53 (Lys382) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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