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Product Name | Human LSD1 Synthetic Peptide |
Description | Human LSD1 Synthetic Peptide. LSD1 is a histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. LSD1 contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. LSD1 demethylates both mono- and tri-methylted 'Lys-4' of histone H3. This protein may play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3 'Lys-4' on nucleosomes and requires the pres |
Size | 50 ug |
Concentration | n/a |
Applications | Blocking Assay: Assay Dependent, Control: Assay Dependent |
Other Names | n/a |
Gene, Accession, CAS # | Entrez: 23028; Uniprot: O60341 |
Catalog # | PEP-0340 |
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Order / More Info | Human LSD1 Synthetic Peptide from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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