产品详情 |
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Antigenic Specificity | CD276 (B7-H3) |
Clone | MJ8 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b |
Format | purified |
Size | 250 µg |
Concentration | n/a |
Applications | Flow Cytometry: Assay-dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD276 (B7-H3) Monoclonal Antibody (MJ8). B7-H3 (CD276) gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 102657; Uniprot: Q8VE98 |
Catalog # | MA5-28242 |
Price | |
Order / More Info | CD276 (B7-H3) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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