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Antigenic Specificity | CD79a |
Clone | JCB117 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1, kappa |
Format | purified |
Size | 500 µL |
Concentration | n/a |
Applications | Flow Cytometry: 2 µg/test, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:100-1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD79a Monoclonal Antibody (JCB117). CD79a is a disulphide-linked heterodimer that includes B29 (CD79b) polypeptide. CD79a is a B lymphocyte antigen receptor with an antigen-specific surface component Ig (immunoglobulin) that associates with Ig-alpha and Ig-beta, necessary elements for the expression and function of the B-cell antigen receptor. CD79a first appears at pre-B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton |
Immunogen | n/a |
Other Names | IGA, MB-1, B-cell antigen receptor complex-associated protein alpha chain, CD79a antigen immunoglobulin-associated alpha, MB-1 membrane glycoprotein |
Gene, Accession # | Entrez: 12518, 973; Uniprot: P11911, P11912 |
Catalog # | MA5-11636 |
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Order / More Info | CD79a Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 16148405, 16919035, 18685486, 20696394 |
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