| 产品详情 |
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| Antigenic Specificity | FOXP3 |
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| Clone | 150D/E4 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | FOXP3 Monoclonal Antibody (150D/E4), eBioscience™. FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis. FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells. Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice. In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-l |
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| Immunogen | n/a |
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| Other Names | AIID, DIETER, Forkhead box P3, foxp3, IPEX, JM2, PIDX, SCURFIN, XPID |
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| Gene, Accession # | Entrez: 20371, 317382, 50943; Uniprot: Q99JB6, Q9BZS1 |
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| Catalog # | 14-4774-80 |
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| Price | |
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| Order / More Info | FOXP3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 18567616, 18769452, 19841181, 22736020, 23482447, 23648563, 26074680, 26414764, 27168826, 27798146, 28389590, 28416194, 28819166 |
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