| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | FOXP3 |
|---|
| Clone | 150D/E4 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, mouse, rat |
|---|
| Isotype | IgG1, kappa |
|---|
| Format | eFluor 660 conjugate |
|---|
| Size | 100 Tests |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 5 µL (0.06 µg)/test |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | FOXP3 Monoclonal Antibody (150D/E4), eFluor 660, eBioscience™. FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis. FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells. Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice. In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, ente |
|---|
| Immunogen | n/a |
|---|
| Other Names | AIID, DIETER, Forkhead box P3, foxp3, IPEX, JM2, PIDX, SCURFIN, XPID |
|---|
| Gene, Accession # | Entrez: 20371, 317382, 50943; Uniprot: Q99JB6, Q9BZS1 |
|---|
| Catalog # | 50-4774-42 |
|---|
| Price | |
|---|
| Order / More Info | FOXP3 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 23482447, 26074680, 26414764, 27168826 |
|---|
| 产品资料 |
|
|