| 产品详情 |
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| Antigenic Specificity | FOXP3 |
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| Clone | 236A/E7 |
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| Host Species | Mouse |
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| Reactive Species | human, nonhuman primate, rhesus monkey |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Frozen): 5 µg/mL, Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: 1-10 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | FOXP3 Monoclonal Antibody (236A/E7), eBioscience™. FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis. FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells. Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice. In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-l |
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| Immunogen | n/a |
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| Other Names | AIID, DIETER, Forkhead box P3, foxp3, IPEX, JM2, PIDX, SCURFIN, XPID |
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| Gene, Accession # | Entrez: 50943, 574303; Uniprot: Q9BZS1 |
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| Catalog # | 14-4777-80 |
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| Price | |
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| Order / More Info | FOXP3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 16304057, 18430198, 18453600, 18567616, 18684941, 18769452, 18941119, 19028999, 19507029, 19542249, 19542441, 19661482, 19845018, 19912254, 20371478, 20617900, 20809047, 21147109, 21347344, 21437244, 21768398, 21876620, 22131334, 22647666, 22718119, 22736020, 23041830, 23189166, 23284620, 23701942, 23876802, 23894725, 24244265, 24466164, 24594700, 24594971, 24741578, 24771328, 24774748, 24978137, 25038256, 25329329, 25359994, 25808375, 25816162, 25949908, 25968569, 26015970, 26209553, 26482032, 26502405, 26517811, 26527522, 26540618, 26769139, 26999600, 27017850, 27039301, 27056325, 27077371, 27246196, 27246829, 27467953, 27473163, 27479084, 27539742, 27708986, 27756099, 27868139, 28290464, 28388539, 28389592, 28811976, 28837142, 28993429, 29166588, 29371976, 29416729 |
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