| 产品详情 |
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| Antigenic Specificity | FOXP3 |
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| Clone | 236A/E7 |
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| Host Species | Mouse |
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| Reactive Species | human, nonhuman primate, rhesus monkey |
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| Isotype | IgG1, kappa |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 25 Tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 5 µL (0.125 µg)/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | FOXP3 Monoclonal Antibody (236A/E7), APC, eBioscience™. FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis. FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells. Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice. In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy |
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| Immunogen | n/a |
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| Other Names | AIID, DIETER, Forkhead box P3, foxp3, IPEX, JM2, PIDX, SCURFIN, XPID |
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| Gene, Accession # | Entrez: 50943, 574303; Uniprot: Q9BZS1 |
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| Catalog # | 17-4777-41 |
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| Price | |
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| Order / More Info | FOXP3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 16304057, 18270368, 18388146, 18453600, 18497876, 18567616, 19717521, 20371478, 20443736, 20617900, 20976449, 21147109, 21569810, 21715555, 22422061, 22457280, 22837179, 23243423, 23319273, 23741502, 23894725, 24386482, 24548868, 24917999, 24978137, 25904524, 26137397, 26482032, 26561546, 26587321, 26854929, 26886923, 26999600, 27077371, 27152621, 27246196, 27389696, 27708986, 27867382, 28159733, 28290464, 28352269, 28993769, 29166588, 29371976 |
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