产品名称 Human TRX Antibody from CREATIVE DIAGNOSTICS
产品货号 DCABH-2760
产品价格 现货询价,电话:010-67529703
产品规格 n/a
产品品牌 CREATIVE DIAGNOSTICS
产品概述
产品详情
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Antigenic SpecificityHuman TRX
CloneKN21-120
Host SpeciesRabbit
Reactive Specieshuman
IsotypeIgG
Formatunconjugated
Sizen/a
Concentrationn/a
ApplicationsWB, ICC/IF, IHC, IP
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DescriptionRabbit Anti-Human TRX monoclonal antibody for WB, ICC/IF, IHC, IP. Thioredoxin (Trx) is a redox protein that is found in several species, such as bacteria, plants and mammals, and contains a conserved active site, consisting of Trp-Cys-Gly-Pro-Cys. Trx has several biological functions. It acts as a hydrogen donor for ribonucleotide reductase, which is critical for DNA synthesis, and modulates the DNA-binding activity of several transcription factors, including NFkB, AP-1, p53, TFIIIC and glucocorticoid receptor. Trx also stimulates cell growth, is an inhibitor of apoptosis and plays a role in the protection against oxidative stress. Drugs that inhibit Trx have antitumor activity, suggesting that Trx is involved in a variety of human diseases, including cancer. TrxR is a ubiquitously expressed flavoprotein that catalyzes the NADPH-dependent reduction of Trx as well as several other oxidized cellular components.
ImmunogenRecombinant Protein
Other Namesn/a
Gene, Accession #Gene ID: 7295, UniProt: P10599
Catalog #DCABH-2760
Price
Order / More InfoHuman TRX Antibody from CREATIVE DIAGNOSTICS
Product Specific Referencesn/a
产品资料