| 产品详情 |
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| Antigenic Specificity | ATP7B |
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| Clone | S62-29 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry (PFA fixed): 1:100, Immunoprecipitation: Assay-Dependent, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ATP7B Monoclonal Antibody (S62-29). This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). |
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| Immunogen | n/a |
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| Other Names | ATP7B, ATPase Cu++ transporting beta polypeptide, ATPase Cu(2+) transporting beta polypeptide, Copper pump 2, Copper transporting ATPase 2, PWD, Toxic milk, tx, WC1, WD, Wilson disease associated protein, WND, WND/140 kDa |
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| Gene, Accession # | Entrez: 11979, 24218, 540; Uniprot: P35670, Q64446, Q64535 |
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| Catalog # | MA5-27719 |
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| Price | |
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| Order / More Info | ATP7B Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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