| 产品详情 |
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| Antigenic Specificity | DOK6 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:1000-1:2500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DOK6 Polyclonal Antibody. DOK-6 (docking protein 6),is a novel member of the Dok-4/5 subclass of the p62 Dok family of intracellular adaptor molecules.Dok-6 is highly expressed in the developing central nervous system and is co-expressed with Ret in several locations, including sympathetic, sensory, and parasympathetic ganglia, as well as in the ureteric buds of the developing kidneys. Pull-down assays using the Dok-6 phosphotyrosine binding (PTB) domain and GDNF-activated Ret indicate that Dok-6 binds to the phosphorylated Ret Tyr(1062) residue. Moreover, ligand activation of Ret resulted in phosphorylation of tyrosine residue(s) located within the unique C terminus of Dok-6 predominantly through a Src-dependent mechanism, indicating that |
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| Immunogen | n/a |
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| Other Names | Docking protein 6; Downstream of tyrosine kinase 6; DOK5L; docking protein 5-like |
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| Gene, Accession # | Entrez: 220164; Uniprot: Q6PKX4 |
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| Catalog # | PA5-59426 |
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| Price | |
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| Order / More Info | DOK6 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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