产品名称 Human DOK1 Antibody from CREATIVE DIAGNOSTICS
产品货号 DCABH-4567
产品价格 现货询价,电话:010-67529703
产品规格 n/a
产品品牌 CREATIVE DIAGNOSTICS
产品概述
产品详情
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Antigenic SpecificityHuman DOK1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Sizen/a
Concentrationn/a
ApplicationsIHC-P
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DescriptionRabbit Anti-Human DOK1 polyclonal antibody for IHC-P. DOK-1 (P62dok, Docking protein 1) is believed to be a mainly cytoplasmic adaptor protein which down-regulates mitogen-activated protein kinase activation, inhibits cell proliferation and transformation, and promotes cell spreading and cell migration. DOK-1 is a major substrate for many tyrosine kinases including c-kit, v-abl, vFPS, EGF, and PDGF. Upon phosphorylation by kinases, DOK-1 forms a complex with ras GTPase-activating protein. Phosphorylation on tyrosine residues by the insulin receptor kinase results in the negative regulation of the insulin signaling pathway. DOK-1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs.
ImmunogenSynthetic peptide
Other Namesn/a
Gene, Accession #Gene ID: 1796, UniProt: Q99704
Catalog #DCABH-4567
Price
Order / More InfoHuman DOK1 Antibody from CREATIVE DIAGNOSTICS
Product Specific Referencesn/a
产品资料