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| Product Name | ML 218 hydrochloride |
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| Description | Selective inhibitor of T-type calcium channels (IC50 values are 270 and 310 nM for Cav3.3 and Cav3.2 respectively in a patch EP assay). Decreases burst activity in STN neurons; reduces cataleptic behaviour in an in vivo rat model of Parkinson's disease. Displays no significant inhibition of L- or N-type calcium channels, Kir6 (KATP) or KV11.1 (hERG) potassium channels. Orally active. Purity 99%. MW (observed): 405.79 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3,5-Dichloro-N-[[(1α,5α,6-exo,6α)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hex-6-yl]methyl]-benzamide hydrochloride |
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| Gene, Accession, CAS # | CAS: 1346233-68-8 |
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| Catalog # | 4507/10 |
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| Order / More Info | ML 218 hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 27596273, 28573241 |
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| 产品资料 |
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