| 产品详情 |
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| Antigenic Specificity | TLR7 |
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| Clone | 4F4 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay Dependent, Western Blot: 1:1000 - 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TLR7 Monoclonal Antibody (4F4). TLR7 is a 1049 amino acid long highly conserved membrane protein belonging to the Toll-like receptor (TLR) family with 27 LRR (leucine-rich) repeats and a TIR domain. TLR7 plays a fundamental role in pathogen recognition and activation of innate immunity. TLR7 is activated by infections with single-stranded RNA viruses, including influenza virus and vesicular stomatitis virus (VSV). TLR7 is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8. TLR7 also acts via MyD88 and TRAF6, leading to NF-kappaB activation, cytokine secretion and the inflammatory response. TLR7 recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infect |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 51284; Uniprot: Q9NYK1 |
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| Catalog # | MA1-81963 |
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| Price | |
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| Order / More Info | TLR7 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 11777010, 16766205, 9393822 |
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