产品详情 |
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Antigenic Specificity | TRADD |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, nonhuman primate, rat |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Flow Cytometry: 1:200, Immunoprecipitation: 1:100, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TRADD Polyclonal Antibody. The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. |
Immunogen | n/a |
Other Names | TNFR1-associated death domain protein; tumor necrosis factor receptor type 1 associated death domain protein; tumor necrosis factor receptor type 1-associated DEATH domain protein; tumor necrosis factor receptor-1-associated protein |
Gene, Accession # | Entrez: 246756, 71609, 8717; Uniprot: Q15628, Q3U0V2 |
Catalog # | PA5-17465 |
Price | |
Order / More Info | TRADD Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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