| 产品详情 |
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| Antigenic Specificity | OX40 |
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| Clone | 7D6 |
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| Host Species | Mouse |
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| Reactive Species | feline, human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay Dependent, Western Blot: 1.0 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | OX40 Monoclonal Antibody (7D6). The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
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| Immunogen | n/a |
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| Other Names | cluster designation 134, TNFRSF4 |
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| Gene, Accession # | Entrez: 493665, 7293; Uniprot: P43489 |
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| Catalog # | MA5-16548 |
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| Price | |
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| Order / More Info | OX40 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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