产品详情 |
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Antigenic Specificity | OX40 |
Clone | 7D6 |
Host Species | Mouse |
Reactive Species | feline, human |
Isotype | IgG1 |
Format | fluorescein (FITC) conjugate |
Size | 100 ug |
Concentration | n/a |
Applications | Flow Cytometry: Neat-1:5 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | OX40 Monoclonal Antibody (7D6), FITC. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
Immunogen | n/a |
Other Names | cluster designation 134, TNFRSF4 |
Gene, Accession # | Entrez: 493665, 7293; Uniprot: P43489 |
Catalog # | MA5-16547 |
Price | |
Order / More Info | OX40 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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