产品详情 |
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Antigenic Specificity | CTNNB1 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 600 µg |
Concentration | 3 mg/ml |
Applications | WB, IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Goat polyclonal antibody to Catenin (cadherin-associated protein), beta 1. Beta Catenin is a 88 kDa protein and is a key downstream effector in the Wnt signalling pathway. It is involved in early embryonic development and tumorigenesis. Beta Catenin is part of a complex of proteins that constitute adherens junctions, necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. This protein anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Detects a band of approximately 95 kDa by Western blot in MNT1 and SH-SY5Y cell lysates. |
Immunogen | Purified recombinant peptide derived from within residues 731 aa to the C-terminus of human beta Catenin produced in E. coli. |
Other Names | beta-Catenin 1, cadherin-associated protein, CTNNB, MRD19, armadillo |
Gene, Accession # | CTNNB1, Gene ID: 1499 |
Catalog # | AB0095-200 |
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Order / More Info | CTNNB1 Antibody from SICGEN ANTIBODIES |
Product Specific References | 1. Balashova OA, Visina O, Borodinsky LN. Development. 2017 Mar 2. PMID:28255006 |
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