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Antigenic Specificity | KDM5B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Alexa Fluor® 647 conjugate |
Size | 100ul |
Concentration | 1ug/ul |
Applications | IF(IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | KDM5B Polyclonal Antibody, Alexa Fluor® 647 Conjugated. • Target Background: Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-ARNTL/BMAL1 heter |
Immunogen | KLH conjugated synthetic peptide derived from human KDM5B/Jarid1B. Immunogen Range: 80-130/1544 |
Other Names | CT31; PLU1; PUT1; PLU-1; JARID1B; PPP1R98; RBBP2H1A; Lysine-specific demethylase 5B; Cancer/testis antigen 31; Histone demethylase JARID1B; Jumonji/ARID domain-containing protein 1B; Retinoblastoma-binding protein 2 homolog 1; RBP2-H1; KDM5B; RBBP2H1 |
Gene, Accession # | Gene ID: 10765, SwissProt: Q9UGL1 |
Catalog # | bs-6139R-A647 |
Price | |
Order / More Info | KDM5B Antibody from BIOSS ANTIBODIES |
Product Specific References | n/a |